A study was conducted to determine the long-term effect of vitamin E and selenium on risk of prostate cancer in relatively healthy men. The observed frequencies are provided below. Using a 0.05 significance level, you need to test the claim that there is a significant association between supplement and prostate cancer.

a. What is the expected frequency of men on both supplements who developed prostate cancer?

b. How much does the cell for men on vitamin E only who developed prostate cancer contribute to the overall test statistic?