The Purpose The purpose for this course work is to learn and practice how to systematize literature data on the topic and to present them in a concise and understandable format. The course work is a literature based research essay with in-depth analysis on the suggested topic. The Format The format of the essay should follow that of review papers adopted by leading scientific journals. You may refer to my paper uploaded on Moodle as an example. Length: 2000-2500 words (excluding the title page and the reference list). Make the file in the MS Word format. Normally, the review should cover at least 3 articles. Spacing: 1.5-line interval Margins: 1.5 cm throughout Font: 12pt Times New Roman The paper should include several sections (each of them is about a particular subtopic): you may name those sections accordingly. The paper should contain a list of the used references. Below is a general guidance for each of the sections (not mandatory and may not be named exactly as shown). Introduction (Thesis) (about 1-2 pages): This is a section, in which you should briefly describe a purpose of your work. Provide some background information, e.g., what is known about the problem and what is not, why this problem is important, etc. Provide respective references to the original sources. Results and Discussion (Evidence and Analysis) (3-4 pages): This is a main section of your paper. It should summarize results from the articles under review. Try to be clear and concise. Remember, “brevity is the soul of wit” (W. Shakespeare). You may use table(s) or/and figure(s) (not more than 2 of each) to present 1 your findings. Discuss your results. What have been found and what remains obscure or still unknown? What are the prospects? Conclusions (1 paragraph, 2-3 sentences)): A brief concluding statement of the previous section. References. You should provide both in-text references and a list of the used references at the end of the essay. Please refer to my article as an example. In preparation of your essay, you are encouraged to use the following sources and databases: the US National Library of Medicine (http://www.nlm.nih.gov/); National Center for Biotechnology Information (http://www.ncbi.nlm.nih.gov/); European Molecular Biological Organization (http://www.embo.org/) and similar world organizations and databases.